Effects of acyl chain length, unsaturation, and pH on thermal stability of model discoidal HDLs.

Effects of Acyl Chain Length, Unsaturation and pH on Thermal Stability of Model Discoidal High-Density Lipoproteins Authors:

Metabolism of apoA-I as lipid-free protein or as component of discoidal and spherical reconstituted HDLs: studies in wild-type and hepatic lipase transgenic rabbits.

OBJECTIVE Apolipoprotein (apo)A-I exists in 3 forms in plasma: as lipid-free apoA-I, as a component of pre-beta-migrating discoidal high density lipoproteins (HDLs), and as a component of alpha-migrating spherical HDLs. This study investigates (1) the in vivo metabolism of apoA-I in each of these forms and (2) the effects of hepatic lipase (HL) on apoA-I metabolism. METHODS AND RESULTS Wild-t...

Effect of acyl chain unsaturation on the packing of model diacylglycerols in simulated monolayers.

In a companion study of the effects of acyl chain unsaturation on a series of model sn-1,2-diacylglycerols (DGs) we showed that individual DGs could adopt one of three energy-minimized conformations depending on the number and location of cis double bonds in the sn-2 chain. Here we show that each of these conformations promotes a distinct type of packing arrangement in a simulated DG monolayer....

Thermal negativity in a two qubit XXX and XX spin chain model in an external magnetic field

In this paper we studied the thermal negativity in a two-qubit XX spin ½ chain model and XXX spin1/2 chain model(isotropic Heisenberg model)spin-1/2 chain subjected to an external magnetic field inz direction. We calculate analytical relation for the thermal negativity for two qubit XX and XXX spinchain models in the external magnetic field. Effects of the magnetic field and temperature on then...

Regulation of membrane proteins by dietary lipids: effects of cholesterol and docosahexaenoic acid acyl chain-containing phospholipids on rhodopsin stability and function.

Purified bovine rhodopsin was reconstituted into vesicles consisting of 1-stearoyl-2-oleoyl phosphatidylcholine or 1-stearoyl-2-docosahexaenoyl phosphatidylcholine with and without 30 mol % cholesterol. Rhodopsin stability was examined using differential scanning calorimetry (DSC). The thermal unfolding transition temperature (T(m)) of rhodopsin was scan rate-dependent, demonstrating the presen...